Nitropyrazoles | Sciact

Nitropyrazoles Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2010, Volume: 59, Number: 9, Pages: 1786-1790 Pages count : 5 DOI: 10.1007/s11172-010-0313-y

Authors

Dalinger I.L. ¹ , Vatsadze I.A. ¹ , Shkineva T.K. ¹ , Kortusov I.O. ² , Popova G.P. ¹ , Kachala V.V. ¹ , Sheveleva S.A. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation
2	D. I. Mendeleev University of Chemical Engineering, 9 Miusskaya pl., 125047, Moscow, Russian Federation

N-Substituted 3,4-dinitropyrazoles, 1,5-dimethyl-3,4-dinitropyrazole and 1-methoxy-methyl-5-methyl-3,4-dinitropyrazole, undergo nucleophilic substitution when reacted with S-, O-, and N-nucleophiles. The substitution occurs regioselectively at the 3-position, affording products in good yields. Anions of N-unsubstituted 3,4-dinitropyrazoles, 1H-3(5)-methyl-4,5(3)-dinitropyrazole and 1H-4,5(3)-dinitropyrazole, also react in water with S-nucleophiles with regioselective substitution of the nitro groups in the position 3(5).

Dalinger I.L. , Vatsadze I.A. , Shkineva T.K. , Kortusov I.O. , Popova G.P. , Kachala V.V. , Sheveleva S.A.
Nitropyrazoles
Russian Chemical Bulletin. 2010. V.59. N9. P.1786-1790. DOI: 10.1007/s11172-010-0313-y WOS Scopus OpenAlex

≡ Web of science:	WOS:000286612600019
≡ Scopus:	2-s2.0-79951733098
≡ OpenAlex:	W2949625448