Synthesis and antibacterial activity of 3,4-dihyhdropyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4-ones

Synthesis and antibacterial activity of 3,4-dihyhdropyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4-ones Full article

Journal

Pharmaceutical Chemistry Journal
ISSN: 0091-150X , E-ISSN: 1573-9031

Output data

Year: 2008, Volume: 42, Number: 9, Pages: 533-535 Pages count : 3 DOI: 10.1007/s11094-009-0168-4

Authors

Kostenko E.S. ¹ , Kaigorodova E.A. ² , Serdyuchenko I.V. ² , Terekhov V.I. ² , Konyushkin L.D. ³

Affiliations

1	Kuban State Technical University, Krasnodar, Russia
2	Kuban State Agricultural University, Krasnodar, Russia
3	Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia

A series of 3,4-dihydropyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4-ones were synthesized by the reaction of ethyl 3-alkyl(aryl)carboxamidothieno[2,3-b]pyridine-2-carboxylates with aliphatic amines. The starting carboxamides were obtained via the reaction of ethyl 3-aminothieno[2,3-b]pyridine-2-carboxylate with acid chlorides. It is established that the synthesized pyridothienopyrimidinones possess antistaphylococcal activity.

Kostenko E.S. , Kaigorodova E.A. , Serdyuchenko I.V. , Terekhov V.I. , Konyushkin L.D.
Synthesis and antibacterial activity of 3,4-dihyhdropyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4-ones
Pharmaceutical Chemistry Journal. 2008. V.42. N9. P.533-535. DOI: 10.1007/s11094-009-0168-4 Scopus OpenAlex

≡ Scopus:	2-s2.0-58849091800
≡ OpenAlex:	W2045971896