Hydrogenation on palladium-containing granulated catalysts 3. Synthesis of aminobenzimidazoles by catalytic hydrogenation of dinitroanilines

Hydrogenation on palladium-containing granulated catalysts 3. Synthesis of aminobenzimidazoles by catalytic hydrogenation of dinitroanilines Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2007, Volume: 56, Number: 6, Pages: 1216-1226 Pages count : 11 DOI: 10.1007/s11172-007-0184-z

Authors

Elkin V.V. ¹ , Tolkacheva L.N. ¹ , Chernysheva N.B. ¹ , Karmanova I.B. ¹ , Konyushkin L.D. ¹ , Semenov V.V. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

Efficient hydrogenation of o-aminonitrobenzenes on palladium-containing granulated carbon catalysts in carboxylic acid solutions was accompanied by cyclization into aminobenzimidazoles. A simple hydrogenation reactor with a fixed gauze holding a reusable granulated catalyst was designed. Acylated and sulfonylated 4(7)-aminobenzimidazoles were obtained. In terms of electronic and geometrical parameters, they are close analogs of biologically active imidazo[1,5,4-e,f ][1,5]benzodiazepines.

Elkin V.V. , Tolkacheva L.N. , Chernysheva N.B. , Karmanova I.B. , Konyushkin L.D. , Semenov V.V.
Hydrogenation on palladium-containing granulated catalysts 3. Synthesis of aminobenzimidazoles by catalytic hydrogenation of dinitroanilines
Russian Chemical Bulletin. 2007. V.56. N6. P.1216-1226. DOI: 10.1007/s11172-007-0184-z WOS Scopus OpenAlex

≡ Web of science:	WOS:000251971700019
≡ Scopus:	2-s2.0-36949026514
≡ OpenAlex:	W2953177024