Synthesis of Pentafluorophenylmethylamines via Silicon Mannich Reaction

Synthesis of Pentafluorophenylmethylamines via Silicon Mannich Reaction Full article

Journal

Organic Letters
ISSN: 1523-7060 , E-ISSN: 1523-7052

Output data

Year: 2005, Volume: 7, Number: 14, Pages: 2913-2915 Pages count : 3 DOI: 10.1021/ol050845l

Authors

Dilman Alexander D. ¹ , Belyakov Pavel A. ¹ , Korlyukov Alexander A. ² , Struchkova Marina I. ¹ , Tartakovsky Vladimir A. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, 119991 Moscow, Leninsky prosp. 47, Russian Federation
2	A. N. Nesmeyanov Institute of Organoelement Compounds, 119991 Moscow, Vavilov str. 28, Russian Federation

The three-component coupling of aldehydes, secondary amines, and methoxytris(pentafluorophenyl)silane, MeOSi(C6F5)3, affording pentafluorophenylmethylamines has been described. The generation of the five-coordinate silicate intermediate is believed to be the key feature responsible for the efficiency of the reaction.

Dilman A.D. , Belyakov P.A. , Korlyukov A.A. , Struchkova M.I. , Tartakovsky V.A.
Synthesis of Pentafluorophenylmethylamines via Silicon Mannich Reaction
Organic Letters. 2005. V.7. N14. P.2913-2915. DOI: 10.1021/ol050845l WOS Scopus OpenAlex

Web of science:	WOS:000230213100028
Scopus:	2-s2.0-22244493902
OpenAlex:	W2950839881

DB	Citing
OpenAlex	28
Scopus	27
Web of science	27