Synthesis and antiproliferative properties of 3,4-diarylpyrrole-2-carboxamides

Synthesis and antiproliferative properties of 3,4-diarylpyrrole-2-carboxamides Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2021, Volume: 70, Number: 3, Pages: 498-509 Pages count : 12 DOI: 10.1007/s11172-021-3115-5

Authors

Silyanova E.A. ¹ , Samet A.V. ¹ , Semenova M.N. ² , Semenov V.V. ¹

Affiliations

1	N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow (Russian Federation)
2	N. K. Kol’tsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russian Federation

A series of 3,4-diarylpyrrole-2-carboxamides was synthesized using the Barton—Zard reaction of nitrostilbenes with ethyl isocyanoacetate in the key stage. The antiproliferative properties of these compounds were studied on a sea urchin embryo model, as well as on 60 human tumor cell lines.

Silyanova E.A. , Samet A.V. , Semenova M.N. , Semenov V.V.
Synthesis and antiproliferative properties of 3,4-diarylpyrrole-2-carboxamides
Russian Chemical Bulletin. 2021. V.70. N3. P.498-509. DOI: 10.1007/s11172-021-3115-5 WOS Scopus OpenAlex

Web of science:	WOS:000633737400012
Scopus:	2-s2.0-85103603405
OpenAlex:	W3147190394

DB	Citing
OpenAlex	10
Web of science	9
Scopus	10