Synthesis of 12-aryl-1-oxo-1,2,3,4,5,12-hexahydroindolo-[2,1-b]quinazoline-6-carbonitriles by recyclization of 11-aryl-1-oxo-2,3,4,5,10b,11-hexahydro-1H-indolo[2,3-b]quinoline-10b-carbonitriles

Synthesis of 12-aryl-1-oxo-1,2,3,4,5,12-hexahydroindolo-[2,1-b]quinazoline-6-carbonitriles by recyclization of 11-aryl-1-oxo-2,3,4,5,10b,11-hexahydro-1H-indolo[2,3-b]quinoline-10b-carbonitriles Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2002, Volume: 51, Number: 10, Pages: 1869-1874 Pages count : 6 DOI: 10.1023/a:1021352502237

Authors

Lichitsky B.V. ¹ , Kozhinov D.V. ¹ , Vorontsova L.G. ¹ , Starikova Z.A. ² , Dudinov A.A. ¹ , Krayushkin M.M. ¹

Affiliations

1	Russian Academy of Sciences, N. D. Zelinsky Institute of Organic Chemistry, Moscow, Russian Federation
2	Russian Academy of Sciences, A. N. Nesmeyanov Institute of Organoelement Compounds, Moscow, Russian Federation

A general and convenient method for the synthesis of 12-aryl-1-oxo-1,2,3,4,5,12-hexahydroindolo[2,1-b]quinazoline-6-carbonitriles was proposed. The method is based on the recyclization of 11-aryl-1-oxo-2,3,4,5,10b,11-hexahydro-1H-indolo[2,3-b]quinoline-10b-carbonitriles. The structure of 12-(3-methoxyphenyl)-8-methyl-1-oxo-1,2,3,4,5,12-hexahydroindolo[2,1-b]quinazoline-6-carbonitrile was studied by X-ray diffraction analysis.

Lichitsky B.V. , Kozhinov D.V. , Vorontsova L.G. , Starikova Z.A. , Dudinov A.A. , Krayushkin M.M.
Synthesis of 12-aryl-1-oxo-1,2,3,4,5,12-hexahydroindolo-[2,1-b]quinazoline-6-carbonitriles by recyclization of 11-aryl-1-oxo-2,3,4,5,10b,11-hexahydro-1H-indolo[2,3-b]quinoline-10b-carbonitriles
Russian Chemical Bulletin. 2002. V.51. N10. P.1869-1874. DOI: 10.1023/a:1021352502237 WOS Scopus OpenAlex

≡ Web of science:	WOS:000180430000012
≡ Scopus:	2-s2.0-0036450885
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