Synthesis of Trifluoromethylated Dithiocarbamates via Photocatalyzed Substitution Reaction: Pentafluoropyridine as Activating Reagent

Synthesis of Trifluoromethylated Dithiocarbamates via Photocatalyzed Substitution Reaction: Pentafluoropyridine as Activating Reagent Full article

Journal

European Journal of Organic Chemistry
ISSN: 1434-193X , E-ISSN: 1099-0690

Output data

Year: 2021, Volume: 2021, Number: 6, Pages: 1007-1010 Pages count : 4 DOI: 10.1002/ejoc.202001572

Authors

Zemtsov Artem A. ¹ , Lunkov Sergey S. ^2,1 , Levin Vitalij V. ¹ , Dilman Alexander D. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Leninsky prosp. 47, 119991 Moscow, Russian Federation
2	Moscow State University Department of Chemistry Leninskie Gory 1–3 119991 Moscow Russian Federation

A method for the synthesis of trifluoromethyl-substituted dithiocarbamates from aldehydes is described. The reaction involves nucleophilic trifluoromethylation, derivatization of the silyloxy-group with pentafluoropyridine, and substitution of the fluorinated pyridinyloxy group by dithiocarbamate anion. The substitution step is performed in the presence of 12-phenyl-12H-benzo[b]phenothiazine and copper cyanide under irradiation of 400 nm LED.

Zemtsov A.A. , Lunkov S.S. , Levin V.V. , Dilman A.D.
Synthesis of Trifluoromethylated Dithiocarbamates via Photocatalyzed Substitution Reaction: Pentafluoropyridine as Activating Reagent
European Journal of Organic Chemistry. 2021. V.2021. N6. P.1007-1010. DOI: 10.1002/ejoc.202001572 WOS Scopus OpenAlex

Web of science:	WOS:000609906100001
Scopus:	2-s2.0-85099773676
OpenAlex:	W3114382807

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OpenAlex	8
Scopus	9
Web of science	9