Reactions of -aminopropionic acid N"-acylhydrazides with carbonyl compounds

Reactions of -aminopropionic acid N"-acylhydrazides with carbonyl compounds Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2004, Volume: 53, Number: 3, Pages: 635-640 Pages count : 6 DOI: 10.1023/b:rucb.0000035649.77800.28

Authors

Smirnov G.A. ¹ , Sizova E.P. ¹ , Luk"yanov O.A. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

The reactions of β-aminopropionic acid N"-acylhydrazides with aromatic and heterocyclic aldehydes and acetone afford compounds that exist in solutions predominantly as mixtures of 2-substituted 3-acylaminotetrahydropyrimidin-4-ones (ATHP) and tautomeric Schiff"s bases. These compounds in the crystalline state probably have structures of ATHP. The ratio of tautomers depends on the type of substituent in the aromatic ring and solvent. The reactions of 2-aryl-3-benzamidotetrahydropyrimidin-4-ones with carboxylic or sulfonic acid chlorides afford derivatives of 1-acyl- and 1-tosyl-3-benzamidotetrahydropyrimidin-4-ones.

Smirnov G.A. , Sizova E.P. , Luk"yanov O.A.
Reactions of -aminopropionic acid N"-acylhydrazides with carbonyl compounds
Russian Chemical Bulletin. 2004. V.53. N3. P.635-640. DOI: 10.1023/b:rucb.0000035649.77800.28 WOS Scopus OpenAlex

≡ Web of science:	WOS:000223566500020
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