Nitropyrazoles. 11. Isomeric 1-methyl-3(5)-nitropyrazole-4-carbonitriles in nucleophilic substitution reactions. Comparative reactivity of the nitro group in positions 3 and 5 of the pyrazole ring

Nitropyrazoles. 11. Isomeric 1-methyl-3(5)-nitropyrazole-4-carbonitriles in nucleophilic substitution reactions. Comparative reactivity of the nitro group in positions 3 and 5 of the pyrazole ring Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2004, Volume: 53, Number: 3, Pages: 580-583 Pages count : 4 DOI: 10.1023/b:rucb.0000035641.63102.14

Authors

Dalinger I.L. ¹ , Zaitsev A.A. ¹ , Shkineva T.K. ¹ , Shevelev S.A. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991 Moscow, Russian Federation

With reactions of isomeric 1-methyl-3-nitro- and 1-methyl-5-nitropyrazole-4-carbonitriles with anionic S-, O-, and N-nucleophiles (RSH, PhOH, and 3,5-dimethyl-4-nitropyrazole in the presence of K2CO3 or MeONa), it was shown that for N-substituted 3(5)-nitropyrazoles, the nitro group in position 5 is much more reactive than in position 3.

Dalinger I.L. , Zaitsev A.A. , Shkineva T.K. , Shevelev S.A.
Nitropyrazoles. 11. Isomeric 1-methyl-3(5)-nitropyrazole-4-carbonitriles in nucleophilic substitution reactions. Comparative reactivity of the nitro group in positions 3 and 5 of the pyrazole ring
Russian Chemical Bulletin. 2004. V.53. N3. P.580-583. DOI: 10.1023/b:rucb.0000035641.63102.14 WOS Scopus OpenAlex

≡ Web of science:	WOS:000223566500012
≡ Scopus:	2-s2.0-4043102628
≡ OpenAlex:	W2106218032