Regioselective C-alkylation of alkyl 4-hydroxy-2-methylthiophene-3-carboxylates with -halo ketones

Regioselective C-alkylation of alkyl 4-hydroxy-2-methylthiophene-3-carboxylates with -halo ketones Научная публикация

Журнал

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Вых. Данные

Год: 2004, Том: 53, Номер: 3, Страницы: 631-634 Страниц : 4 DOI: 10.1023/b:rucb.0000035648.41262.77

Авторы

Krayushkin M.M. ¹ , Shirinian V.Z. ¹ , Nikalin D.M. ¹ , Shimkin A.A. ¹

Организации

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

Regioselective C- or O-alkylation of alkyl 4-hydroxy-2-methylthiophene-3-carboxylates with α-halo ketones is possible, depending on the solvent nature. A convenient preparative method of C-alkylation was proposed and previously not easily accessible β-hydroxythiophene derivatives were synthesized.

Krayushkin M.M. , Shirinian V.Z. , Nikalin D.M. , Shimkin A.A.
Regioselective C-alkylation of alkyl 4-hydroxy-2-methylthiophene-3-carboxylates with -halo ketones
Russian Chemical Bulletin. 2004. V.53. N3. P.631-634. DOI: 10.1023/b:rucb.0000035648.41262.77 WOS Scopus OpenAlex

Web of science:	WOS:000223566500019
Scopus:	2-s2.0-4043154921
OpenAlex:	W2950414101

БД	Цитирований
OpenAlex	4
Scopus	7
Web of science	7