2-(2-(4-Methoxyphenyl)-4,9-dimethyl-7-oxo-7H-furo[2,3-f]chromen-3-yl)acetic Acid

2-(2-(4-Methoxyphenyl)-4,9-dimethyl-7-oxo-7H-furo[2,3-f]chromen-3-yl)acetic Acid Full article

Journal

Molbank
ISSN: 1422-8599

Output data

Year: 2021, Volume: 2021, Number: 4, Article number : M1304, Pages count : DOI: 10.3390/m1304

Authors

Lichitsky Boris V. ¹ , Komogortsev Andrey N. ¹ , Melekhina Valeriya G. ¹

Affiliations

1	N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Science, Leninsky Pr., 47, 119991 Moscow, Russia

For the first time, we describe a new approach towards the synthesis of previously unknown 2-(2-(4-methoxyphenyl)-4,9-dimethyl-7-oxo-7H-furo[2,3-f]chromen-3-yl)acetic acid. The presented method is based on the multicomponent condensation of 5-hydroxy-4,7-dimethyl-2H-chromen-2-one, 4-methoxyphenylglyoxal and Meldrum’s acid. It was shown that the studied reaction proceeds in two steps including the initial interaction of starting materials in MeCN and the final formation of furylacetic acid moiety in acidic media. The structures of the obtained compound were established by 1H, 13C-NMR spectroscopy and high-resolution mass spectrometry.

Lichitsky B.V. , Komogortsev A.N. , Melekhina V.G.
2-(2-(4-Methoxyphenyl)-4,9-dimethyl-7-oxo-7H-furo[2,3-f]chromen-3-yl)acetic Acid
Molbank. 2021. V.2021. N4. M1304 . DOI: 10.3390/m1304 WOS Scopus OpenAlex

Web of science:	WOS:000735568000001
Scopus:	2-s2.0-85121309376
OpenAlex:	W4200320533

DB	Citing
OpenAlex	6
Scopus	5
Web of science	2