Catalytic System for Cross-Coupling of Heteroaryl Iodides with a Nitronyl Nitroxide Gold Derivative at Room Temperature

Catalytic System for Cross-Coupling of Heteroaryl Iodides with a Nitronyl Nitroxide Gold Derivative at Room Temperature Full article

Journal

Molecules
ISSN: 1420-3049

Output data

Year: 2023, Volume: 28, Number: 22, Article number : 7661, Pages count : DOI: 10.3390/molecules28227661

Authors

Zayakin Igor ¹ , Romanenko Galina ² , Bagryanskaya Irina ³ , Ugrak Bogdan ¹ , Fedin Matvey ² , Tretyakov Evgeny ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Leninsky Ave. 47, Moscow 119991, Russia
2	International Tomography Center, Institutskaya Str. 3a, Novosibirsk 630090, Russia
3	N. N. Vorozhtsov Institute of Organic Chemistry, 9 Ac. Lavrentiev Avenue, Novosibirsk 630090, Russia

A simple and highly effective methodology for the cross-coupling of heteroaryl iodides with NN–AuPPh3 at room temperature is reported. The protocol is based on a novel catalytic system consisting of Pd2(dba)3·CHCl3 and the phosphine ligand MeCgPPh having an adamantane-like framework. The present protocol was found to be well compatible with various heteroaryl iodides, thus opening new horizons in directed synthesis of functionalized nitronyl nitroxides and high-spin molecules.

Zayakin I. , Romanenko G. , Bagryanskaya I. , Ugrak B. , Fedin M. , Tretyakov E.
Catalytic System for Cross-Coupling of Heteroaryl Iodides with a Nitronyl Nitroxide Gold Derivative at Room Temperature
Molecules. 2023. V.28. N22. 7661 . DOI: 10.3390/molecules28227661 WOS Scopus OpenAlex

Web of science:	WOS:001119655400001
Scopus:	2-s2.0-85177805454
OpenAlex:	W4388832587

DB	Citing
OpenAlex	6
Scopus	5
Web of science	3