Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees

Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees Full article

Journal

Molecules
ISSN: 1420-3049

Output data

Year: 2020, Volume: 25, Number: 8, Article number : 1954, Pages count : DOI: 10.3390/molecules25081954

Authors

Yaremenko Ivan A ^1,2 , Syromyatnikov Mikhail Y ³ , Radulov Peter S ^1,2 , Belyakova Yulia Yu ^1,2 , Fomenkov Dmitriy I ² , Popov Vasily N ^3,4 , Terent'ev Alexander O ^1,2

Affiliations

1	All-Russian Research Institute for Phytopathology, B. Vyazyomy, Moscow Region 143050, Russia
2	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 119991, Russia
3	Department of Genetics, Cytology and Bioengineering, Voronezh State University, Voronezh 394018, Russia
4	Voronezh State University of Engineering Technologies, Voronezh 394036, Russia

In recent years, the number of pollinators in the world has significantly decreased. A possible reason for this is the toxic effects of agrochemicals reducing the immunity of insects that leads to their increased susceptibility to pathogens. Ascosphaera apis is a dangerous entomopathogenic fungus, afflicting both honeybees and bumblebees. We investigated fungicide activity of cyclic synthetic peroxides against A. apis isolated from Bombus terrestris L. The peroxides exhibited high mycelium growth inhibition of A. apis up to 94–100% at concentration 30 mg/L. EC50 values were determined for the most active peroxides. Two peroxides showed higher antifungal activity against A. apis than the commercial fungicide Triadimefon. The studied peroxides did not reduce the ability of bumblebees to fly and did not lead to the death of bumblebees. A new field of application for peroxides was disclosed.

Yaremenko I.A. , Syromyatnikov M.Y. , Radulov P.S. , Belyakova Y.Y. , Fomenkov D.I. , Popov V.N. , Terent'ev A.O.
Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees
Molecules. 2020. V.25. N8. 1954 . DOI: 10.3390/molecules25081954 WOS Scopus OpenAlex

Web of science:	WOS:000534617500084
Scopus:	2-s2.0-85083804779
OpenAlex:	W3020611811

DB	Citing
OpenAlex	26
Scopus	20
Web of science	19