Dehydration of isoxazoline N-oxides under electrophilic conditions – An alternative approach toward 3-haloisoxazoles

Dehydration of isoxazoline N-oxides under electrophilic conditions – An alternative approach toward 3-haloisoxazoles Научная публикация

Журнал

Tetrahedron Letters
ISSN: 0040-4039 , E-ISSN: 1873-3581

Вых. Данные

Год: 2021, Том: 73, Номер статьи : 153106, Страниц : DOI: 10.1016/j.tetlet.2021.153106

Авторы

Fadeeva Anastasia A. ^1,2 , Ioffe Sema L. ² , Tabolin Andrey A. ²

Организации

1	Higher Chemical College, D. Mendeleev University of Chemical Technology of Russia, Miusskaya sq. 9, Moscow 125047, Russia
2	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky prosp. 47, Moscow 119991, Russia

A new method was developed for the synthesis of fully substituted 3-haloisoxazoles. This process includes the synthesis of isoxazoline N-oxides from α-halonitroalkenes and subsequent dehydration mediated by the silyl triflate/triethylamine system.

Fadeeva A.A. , Ioffe S.L. , Tabolin A.A.
Dehydration of isoxazoline N-oxides under electrophilic conditions – An alternative approach toward 3-haloisoxazoles
Tetrahedron Letters. 2021. V.73. 153106 . DOI: 10.1016/j.tetlet.2021.153106 WOS Scopus OpenAlex

≡ Web of science:	WOS:000656983400014
≡ Scopus:	2-s2.0-85105098042
≡ OpenAlex:	W3158147580