Nitropyrazoles. 1. Synthesis, transformations, and physicochemical properties of nitro derivatives of 1H,4H-pyrazolo[4,3-c]pyrazole

Nitropyrazoles. 1. Synthesis, transformations, and physicochemical properties of nitro derivatives of 1H,4H-pyrazolo[4,3-c]pyrazole Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 1993, Volume: 42, Number: 6, Pages: 1063-1068 Pages count : 6 DOI: 10.1007/bf00704200

Authors

Shevelev S.A. ¹ , Dalinger I.L. ¹ , Shkineva T.K. ¹ , Ugrak B.I. ¹ , Gulevskaya V.I. ¹ , Kanishchev M.I. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 117913, Moscow, Russian Federation

A method of synthesizing nitro derivatives of lH,4H-pyrazolo[4,3-c]pyrazole is developed, and some of its transformations are studied. 3-Methyl-6-nitro-, 3-carboxy(methoxy-carbonyl, carbamoyl)-6-nitro-, 3-amino-6-nitro-, 3-nitro-, 3,6-dinitro-, 1,4-diacetonyl-3,6-dinitro-, and lH,4H-3-aminopyrazolo[4,3-c]pyrazoles were obtained from 1H,4H-3 -methylpyrazolo[4,3-c]pyrazole. Unsubstituted 1H,4H-pyrazolo[4,3-c]pyrazole, the first member of this series, was obtained for the first time. The compounds prepared were characterized by1H,13C,14N, and15N NMR spectroscopy. NH-Acidity and basicity of the series of pyrazolo[4,3-c]pyrazoles synthesized is studied and the effect of the fused pyrazole ring on these properties is examined.

Shevelev S.A. , Dalinger I.L. , Shkineva T.K. , Ugrak B.I. , Gulevskaya V.I. , Kanishchev M.I.
Nitropyrazoles. 1. Synthesis, transformations, and physicochemical properties of nitro derivatives of 1H,4H-pyrazolo[4,3-c]pyrazole
Russian Chemical Bulletin. 1993. V.42. N6. P.1063-1068. DOI: 10.1007/bf00704200 WOS Scopus OpenAlex

≡ Web of science:	WOS:A1993NK88500022
≡ Scopus:	2-s2.0-21344487710
≡ OpenAlex:	W2335326170