Synthesis of allomaltol containing terarylenes with imidazole N -oxides bridge fragment

Synthesis of allomaltol containing terarylenes with imidazole N -oxides bridge fragment Full article

Journal

Synthetic Communications
ISSN: 1532-2432 , E-ISSN: 0039-7911

Output data

Year: 2024, Volume: 54, Number: 6, Pages: 460-470 Pages count : 11 DOI: 10.1080/00397911.2024.2310522

Authors

Milyutin Constantine V. ¹ , Komogortsev Andrey N. ¹ , Lichitsky Boris V. ¹ , Melekhina Valeriya G. ¹

Affiliations

1	N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Science, Moscow, Russian Federation

Method for the synthesis of previously unknown imidazole N-oxides bearing allomaltol unit has been elaborated. The presented approach is based on multicomponent condensation of corresponding oximes containing aroyl and 3-hydroxypyran-4-one fragments with various aldehydes and amines. The advantages of considered method are easily available starting compounds, atom economy, simple experimental procedure including isolation of the final products without column chromatography. The synthetic utility of prepared N-oxides was demonstrated by its further conversion to corresponding 2-chloroimidazole and 2-phenylaminoimidazole derivatives.

Milyutin C.V. , Komogortsev A.N. , Lichitsky B.V. , Melekhina V.G.
Synthesis of allomaltol containing terarylenes with imidazole N -oxides bridge fragment
Synthetic Communications. 2024. V.54. N6. P.460-470. DOI: 10.1080/00397911.2024.2310522 WOS Scopus OpenAlex

Web of science:	WOS:001156493700001
Scopus:	2-s2.0-85184227376
OpenAlex:	W4391480148

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