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Lipopolysaccharide of the Yersinia pseudotuberculosis Complex Review

Journal Biomolecules
ISSN: 2218-273X
Output data Year: 2021, Volume: 11, Number: 10, Article number : 1410, Pages count : DOI: 10.3390/biom11101410
Authors Knirel Yuriy A 1 , Anisimov Andrey P 2 , Kislichkina Angelina A 2 , Kondakova Anna N 1 , Bystrova Olga V 1 , Vagaiskaya Anastasia S 2 , Shatalin Konstantin Y 3 , Shashkov Alexander S 1 , Dentovskaya Svetlana V 2
Affiliations
1 Laboratory of Carbohydrate Chemistry, N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russia.
2 Laboratory for Plague Microbiology, Especially Dangerous Infections Department, State Research Center for Applied Microbiology and Biotechnology, 142279 Obolensk, Russia
3 Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA

Abstract: Lipopolysaccharide (LPS), localized in the outer leaflet of the outer membrane, serves as the major surface component of the Gram-negative bacterial cell envelope responsible for the activation of the host’s innate immune system. Variations of the LPS structure utilized by Gram-negative bacteria promote survival by providing resistance to components of the innate immune system and preventing recognition by TLR4. This review summarizes studies of the biosynthesis of Yersinia pseudotuberculosis complex LPSs, and the roles of their structural components in molecular mechanisms of yersiniae pathogenesis and immunogenesis.
Cite: Knirel Y.A. , Anisimov A.P. , Kislichkina A.A. , Kondakova A.N. , Bystrova O.V. , Vagaiskaya A.S. , Shatalin K.Y. , Shashkov A.S. , Dentovskaya S.V.
Lipopolysaccharide of the Yersinia pseudotuberculosis Complex
Biomolecules. 2021. V.11. N10. 1410 . DOI: 10.3390/biom11101410 WOS Scopus OpenAlex
Identifiers:
Web of science: WOS:000712225800001
Scopus: 2-s2.0-85115602369
OpenAlex: W3203951521
Citing:
DB Citing
OpenAlex 16
Scopus 15
Web of science 15
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