Diastereoselective synthesis of pyrimido[1,2-a][1,3,5]triazines based on the Biginelli reaction

Diastereoselective synthesis of pyrimido[1,2-a][1,3,5]triazines based on the Biginelli reaction Full article

Journal

Tetrahedron
ISSN: 0040-4020 , E-ISSN: 1464-5416

Output data

Year: 2023, Volume: 134, Article number : 133298, Pages count : DOI: 10.1016/j.tet.2023.133298

Authors

Van Quy Do ¹ , Kruzhilin Alexey A. ¹ , Stolpovskaya Nadezhda V. ¹ , Baranin Sergey V. ² , Prezent Mikhail A. ² , Minyaev Mikhail E. ² , Shikhaliev Khidmet S. ¹

Affiliations

1	Voronezh State University, 394018, Voronezh, Russian Federation
2	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Prosp, 119991, Moscow, Russian Federation

A general diastereoselective synthesis of pyrimido[1,2-a][1,3,5]triazine derivatives based on the Biginelli reaction, with the participation of amidinothiourea, arylaldehydes and alkyl acetoacetate (acetylacetone) has been developed.

Van Quy D. , Kruzhilin A.A. , Stolpovskaya N.V. , Baranin S.V. , Prezent M.A. , Minyaev M.E. , Shikhaliev K.S.
Diastereoselective synthesis of pyrimido[1,2-a][1,3,5]triazines based on the Biginelli reaction
Tetrahedron. 2023. V.134. 133298 . DOI: 10.1016/j.tet.2023.133298 WOS Scopus OpenAlex

≡ Web of science:	WOS:000951049400001
≡ Scopus:	2-s2.0-85147571602
≡ OpenAlex:	W4319066238