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Human influenza virus recognition of sialyloligosaccharides Full article

Journal FEBS Letters
ISSN: 0014-5793 , E-ISSN: 1873-3468
Output data Year: 1995, Volume: 366, Number: 1, Pages: 57-60 Pages count : 4 DOI: 10.1016/0014-5793(95)00488-u
Authors Gambaryan A.S. 1 , Piskarev V.E. 2 , Yamskov I.A. 2 , Sakharov A.M. 3 , Tuzikov A.B. 4 , Bovin N.V. 4 , Nifant'ev N.E. 3 , Matrosovich M.N. 1
Affiliations
1 M.P. Chumakov Institute of Poliomyelitis and Viral Encephalitides, Russian Academy of Medical Sciences, 142 782, Moscow Region, Russian Federation
2 Institute of Food Substanses, Russian Academy of Sciences, Vavilov st. 28, 117813 Moscow, Russian Federation
3 Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky pr., 47, 117 913 Moscow, Russian Federation
4 Shemyakin Institute of Bio-Organic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya, 16/10, 117 871 Moscow, Russian Federation

Abstract: Sialic acids are essential components of cell-surface receptors utilized by influenza viruses. To evaluate the recognition of asialic sugar parts of the receptor, three representative strains of human influenza A and B viruses were tested for their binding of a panel of sialyloligosaccharides. The highest affinity binding carbohydrate determinants recognized by the viruses in a context of different core structures were Neu5Acα2-3Gal for the type B virus, Neu5Acα2-6Gal for the H3 subtype virus, and Neu5Acα2-6Ga/β1-4GlcNAc for the H1 subtype virus. Penultimate to these determinants parts of sialyloligosaccharides studied either contributed less significantly to the binding affinity, or interfered with the binding.
Cite: Gambaryan A.S. , Piskarev V.E. , Yamskov I.A. , Sakharov A.M. , Tuzikov A.B. , Bovin N.V. , Nifant'ev N.E. , Matrosovich M.N.
Human influenza virus recognition of sialyloligosaccharides
FEBS Letters. 1995. V.366. N1. P.57-60. DOI: 10.1016/0014-5793(95)00488-u WOS Scopus OpenAlex
Identifiers:
≡ Web of science: WOS:A1995RD04900014
≡ Scopus: 2-s2.0-0029026217
≡ OpenAlex: W2171988948
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