Synthesis of Amides Based on Biologically Active (5Z,9Z)-Eicosa-5,9-dienoic Acid

Synthesis of Amides Based on Biologically Active (5Z,9Z)-Eicosa-5,9-dienoic Acid Full article

Journal

Russian Journal of Organic Chemistry
ISSN: 1608-3393 , E-ISSN: 1070-4280

Output data

Year: 2024, Volume: 60, Number: 3, Pages: 437-441 Pages count : 5 DOI: 10.1134/s1070428024030102

Authors

Makarova E.Kh. ¹ , Makarov A.A. ¹ , Dzhemilev U.M. ² , D’yakonov V.A. ²

Affiliations

1	Institute of Petrochemistry and Catalysis, Ufa Federal Research Center, Russian Academy of Sciences, Ufa, 450075 Russia
2	Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991, Moscow, Russia

New amides of (5Z,9Z)-eicosa-5,9-dienoic acid, which is a highly active topoisomerase I/II inhibitor, were synthesized via Cp2TiCl2-catalyzed intermolecular cross-cyclomagnesiation of aliphatic and oxygen-containing 1,2-dienes as the key step.

Makarova E.K. , Makarov A.A. , Dzhemilev U.M. , D’yakonov V.A.
Synthesis of Amides Based on Biologically Active (5Z,9Z)-Eicosa-5,9-dienoic Acid
Russian Journal of Organic Chemistry. 2024. V.60. N3. P.437-441. DOI: 10.1134/s1070428024030102 WOS Scopus OpenAlex

Web of science:	WOS:001245948700012
Scopus:	2-s2.0-85193717290
OpenAlex:	W4397291061

DB	Citing
OpenAlex	3
Scopus	3
Web of science	3