Synthesis of lysine-containing fragments of the Proteus mirabilis O27 O-specific polysaccharide and neoglyco- conjugates therefrom

Synthesis of lysine-containing fragments of the Proteus mirabilis O27 O-specific polysaccharide and neoglyco- conjugates therefrom Full article

Journal

Carbohydrate Research
ISSN: 1873-426X , E-ISSN: 0008-6215

Output data

Year: 1992, Volume: 225, Number: 2, Pages: 279-289 Pages count : 11 DOI: 10.1016/s0008-6215(00)90501-9

Authors

Chernyak Anatoly Ya. ¹ , Kononov Leonid O. ¹ , Krishna Palakodety Radha ^1,2 , Kochetkov Nikolay K. ¹ , Rao Alla V.Rama ²

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Academy of Sciences of the U.S.S.R., Moscow.
2	Indian Institute of Chemical Technology, Hyderabad 500 007 India

Amide-linked lysine mono- and di-uronic acid fragments of the O-specific polysaccharide from P. mirabilis O27 have been synthesised. Nε-Boc-l-lysine tert-butyl ester was condensed with 2-azidoethyl glycosides of glucuronic acid and β-d-GlcpNAc-(1 → 3)-β-d-GlcpA. Transformation of the products into 2-acrylamidoethyl glycosides, followed by deprotection using trifluoroacetic acid, gave the target monomers that were converted into high-molecular-weight copolymer-type neoglycoconjugates.

Chernyak A.Y. , Kononov L.O. , Krishna P.R. , Kochetkov N.K. , Rao A.V.R.
Synthesis of lysine-containing fragments of the Proteus mirabilis O27 O-specific polysaccharide and neoglyco- conjugates therefrom
Carbohydrate Research. 1992. V.225. N2. P.279-289. DOI: 10.1016/s0008-6215(00)90501-9 WOS Scopus OpenAlex

Web of science:	WOS:A1992HJ35600007
Scopus:	2-s2.0-0027108526
OpenAlex:	W1976031419

DB	Citing
OpenAlex	11
Scopus	13
Web of science	15