A convenient synthesis of 3-substituted 5-guanidino-1,2,4-oxadiazoles

A convenient synthesis of 3-substituted 5-guanidino-1,2,4-oxadiazoles Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 1994, Volume: 43, Number: 1, Pages: 114-117 Pages count : 4 DOI: 10.1007/bf00699147

Authors

Yarovenko V.N. ¹ , Shirinyan V.Z. ¹ , Zavarzin I.V. ¹ , Krayushkin M.M. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences, Moscow, Russian Federation

The reaction of amidoximes with cyanoguanidine in the presence of Lewis acids affords 3-substituted 5-guanidino-1,2,4-oxadiazoles. A study of the reaction of15N-labeled chloroacetamidoxime with cyanoguanidine showed that the formation of the oxadiazole ring occursvia the elimination of the amino group from the amidoxime fragment. 1,2,4-Oxadiazoles bearing the imidazole or pyrimidine moiety were synthesized.

Yarovenko V.N. , Shirinyan V.Z. , Zavarzin I.V. , Krayushkin M.M.
A convenient synthesis of 3-substituted 5-guanidino-1,2,4-oxadiazoles
Russian Chemical Bulletin. 1994. V.43. N1. P.114-117. DOI: 10.1007/bf00699147 WOS Scopus OpenAlex

Web of science:	WOS:A1994PX98300022
Scopus:	2-s2.0-21844521051
OpenAlex:	W1971315168

DB	Citing
OpenAlex	10
Scopus	11
Web of science	10