Tandem acid-promoted intramolecular azide-hydrazone electrocyclization/hydrolysis approach for the synthesis of N-Aminotetrazoles Научная публикация
| Журнал |
Tetrahedron
ISSN: 0040-4020 , E-ISSN: 1464-5416 |
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| Вых. Данные | Год: 2022, Том: 103, Номер статьи : 132563, Страниц : DOI: 10.1016/j.tet.2021.132563 | ||||||||
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Реферат:
A general method for the synthesis of a series of previously unknown N-(heteroaryl)- and N-(aryl)aminotetrazoles through the tandem electrocyclization/hydrolysis of azidohydrazones was accomplished. The described protocol was suitable for a wide array of the target N-substituted aminotetrazoles which were prepared in good to high yields under smooth reaction conditions. Importantly, the presented approach is considered as a direct route to 1,2,5-oxadiazole-substituted aminotetrazole derivatives in good and high yields and may be realized on a gram scale. Therefore, facile synthesis of N-(heteroaryl)- and N-(aryl)aminotetrazoles unveils novel opportunities to study application prospectives of these compounds as functional materials or drug candidates.
Библиографическая ссылка:
Titenkova K.Y.
, Shaferov A.V.
, Larin A.A.
, Epishina M.A.
, Kulikov A.S.
, Ananyev I.V.
, Fershtat L.L.
Tandem acid-promoted intramolecular azide-hydrazone electrocyclization/hydrolysis approach for the synthesis of N-Aminotetrazoles
Tetrahedron. 2022. V.103. 132563 . DOI: 10.1016/j.tet.2021.132563 WOS Scopus OpenAlex
Tandem acid-promoted intramolecular azide-hydrazone electrocyclization/hydrolysis approach for the synthesis of N-Aminotetrazoles
Tetrahedron. 2022. V.103. 132563 . DOI: 10.1016/j.tet.2021.132563 WOS Scopus OpenAlex
Идентификаторы БД:
| Web of science: | WOS:000727184000016 |
| Scopus: | 2-s2.0-85119447084 |
| OpenAlex: | W3212191055 |