Novel one-pot approach to 2-aminofuran derivatives via multicomponent reaction of 3-hydroxy-4H-pyran-4-ones, α-ketoaldehydes and methylene active nitriles Научная публикация
| Журнал |
Tetrahedron Letters
ISSN: 0040-4039 , E-ISSN: 1873-3581 |
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| Вых. Данные | Год: 2020, Том: 61, Номер: 41, Номер статьи : 152384, Страниц : DOI: 10.1016/j.tetlet.2020.152384 | ||
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Реферат:
A novel efficient one-pot method for the preparation of 2-aminofurans was developed based on multicomponent reaction of 3-hydroxy-4H-pyran-4-ones, α-ketoaldehydes and methylene active nitriles. A distinctive feature of the proposed approach is the formation of 2-aminofurans in contrast to related literature methods leading to 2-aminopyrans. The advantages of this synthesis include high yields, mild reaction conditions, atom economy and easy workup procedure, which can avoid chromatographic purifications. The structure of one of the 2-aminofuran derivatives was determined by X-ray diffraction.
Библиографическая ссылка:
Komogortsev A.N.
, Melekhina V.G.
, Lichitsky B.V.
, Minyaev M.E.
Novel one-pot approach to 2-aminofuran derivatives via multicomponent reaction of 3-hydroxy-4H-pyran-4-ones, α-ketoaldehydes and methylene active nitriles
Tetrahedron Letters. 2020. V.61. N41. 152384 . DOI: 10.1016/j.tetlet.2020.152384 WOS Scopus OpenAlex
Novel one-pot approach to 2-aminofuran derivatives via multicomponent reaction of 3-hydroxy-4H-pyran-4-ones, α-ketoaldehydes and methylene active nitriles
Tetrahedron Letters. 2020. V.61. N41. 152384 . DOI: 10.1016/j.tetlet.2020.152384 WOS Scopus OpenAlex
Идентификаторы БД:
| Web of science: | WOS:000573218900011 |
| Scopus: | 2-s2.0-85090847713 |
| OpenAlex: | W3080571424 |