2-(5-Acetyl-7-methoxy-2-(4-methoxyphenyl)benzofuran-3-yl)acetic Acid | Sciact

2-(5-Acetyl-7-methoxy-2-(4-methoxyphenyl)benzofuran-3-yl)acetic Acid Научная публикация

Журнал

Molbank
ISSN: 1422-8599

Вых. Данные

Год: 2022, Том: 2022, Номер: 2, Номер статьи : M1357, Страниц : DOI: 10.3390/m1357

Авторы

Lichitsky Boris V. ¹ , Komogortsev Andrey N. ¹ , Melekhina Valeriya G. ¹

Организации

1	N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Science, Leninsky Pr., 47, 119991 Moscow, Russia

We elaborated a convenient one-step approach for the synthesis of previously unknown 2-(5-acetyl-7-methoxy-2-(4-methoxyphenyl)benzofuran-3-yl)acetic acid. The suggested protocol includes the multicomponent reaction of acetovanillone, 4-methoxyphenylglyoxal and Meldrum’s acid. We have demonstrated that the considered reaction is a one-pot telescoped process including the preliminary condensation of the components in MeCN followed by acid-catalyzed cyclization. The structure of the synthesized product was confirmed by 1H, 13C-NMR spectroscopy and high-resolution mass-spectrometry.

Lichitsky B.V. , Komogortsev A.N. , Melekhina V.G.
2-(5-Acetyl-7-methoxy-2-(4-methoxyphenyl)benzofuran-3-yl)acetic Acid
Molbank. 2022. V.2022. N2. M1357 . DOI: 10.3390/m1357 WOS Scopus OpenAlex

Web of science:	WOS:000816677500001
Scopus:	2-s2.0-85128481277
OpenAlex:	W4225597918

БД	Цитирований
OpenAlex	2
Scopus	3
Web of science	1