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2,4-Diamino-5-(5-amino-3-oxo-2,3-dihydro-1H-pyrazol-4-yl)-5H-chromeno[2,3-b]pyridine-3-carbonitrile Научная публикация

Журнал Molbank
ISSN: 1422-8599
Вых. Данные Год: 2022, Том: 2022, Номер: 3, Номер статьи : M1399, Страниц : DOI: 10.3390/m1399
Авторы Ryzhkova Yuliya E. 1 , Elinson Michail N. 1
Организации
1 N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences, 47 Leninsky Prospekt, 119991 Moscow, Russia

Реферат: The one-pot synthesis methodology has become the leading atom-economical approach for various chemical transformations in a single pot, without purifying intermediate compounds. Chromeno[2,3-b]pyridines are an important class of heterocyclic compounds with versatile biological profiles and other different applications The 5-aminopyrazole system represents a significant heterocyclic template that has gained considerable interest because of its long history of use in the pharmaceutical and agrochemical industries. In this communication, the one-pot transformation of salicylaldehyde, malononitrile dimer, and 2-cyanoacetohydrazide in an ethanol/pyridine mixture was investigated to provide 2,4-diamino-5-(5-amino-3-oxo-2,3-dihydro-1H-pyrazol-4-yl)-5H-chromeno[2,3-b]pyridine-3-carbonitrile in good yield. The structure of the novel compound was confirmed by means of elemental analysis, mass-, nuclear magnetic resonance, and infrared spectroscopy.
Библиографическая ссылка: Ryzhkova Y.E. , Elinson M.N.
2,4-Diamino-5-(5-amino-3-oxo-2,3-dihydro-1H-pyrazol-4-yl)-5H-chromeno[2,3-b]pyridine-3-carbonitrile
Molbank. 2022. V.2022. N3. M1399 . DOI: 10.3390/m1399 WOS Scopus OpenAlex
Идентификаторы БД:
≡ Web of science: WOS:000859522700001
≡ Scopus: 2-s2.0-85133680498
≡ OpenAlex: W4283790738
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