NOBF4-Mediated Assembly of the Sydnone Imine Scaffold in the Synthesis of Double Nitric Oxide Donors Научная публикация
| Журнал |
Synthesis-Stuttgart
ISSN: 1437-210X , E-ISSN: 0039-7881 |
||
|---|---|---|---|
| Вых. Данные | Год: 2023, Том: 55, Номер: 12, Страницы: 1863-1874 Страниц : 12 DOI: 10.1055/a-2011-7264 | ||
| Авторы |
|
||
| Организации |
|
Реферат:
A direct approach toward the construction of furoxan-sydnone imine double NO-donors involving the NOBF4-mediated nitrosation–cyclization sequence of α-amino nitriles as a key synthetic step was developed. The described protocol excludes the isolation of carcinogenic N-nitrosamines, operates broad substrate scope, and enables the preparation of fully substituted sydnone imines linked to the furoxan ring via different linkers or directly through C–C bond. Synthesized library of furoxan-sydnone imine hybrids demonstrated a promising ability to release NO in a wide range of concentrations which is useful for various biomedical insights.
Библиографическая ссылка:
Shuvaev A.
, Zhilin E.
, Fershtat L.
NOBF4-Mediated Assembly of the Sydnone Imine Scaffold in the Synthesis of Double Nitric Oxide Donors
Synthesis-Stuttgart. 2023. V.55. N12. P.1863-1874. DOI: 10.1055/a-2011-7264 WOS Scopus OpenAlex
NOBF4-Mediated Assembly of the Sydnone Imine Scaffold in the Synthesis of Double Nitric Oxide Donors
Synthesis-Stuttgart. 2023. V.55. N12. P.1863-1874. DOI: 10.1055/a-2011-7264 WOS Scopus OpenAlex
Идентификаторы БД:
| Web of science: | WOS:000936625800001 |
| Scopus: | 2-s2.0-85159292390 |
| OpenAlex: | W4315778239 |