Synthesis of Pseudooligosaccharides Related to the Capsular Phosphoglycan of Haemophilus influenzae Type a Научная публикация
| Журнал |
Molecules
ISSN: 1420-3049 |
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| Вых. Данные | Год: 2023, Том: 28, Номер: 15, Номер статьи : 5688, Страниц : DOI: 10.3390/molecules28155688 | ||
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Реферат:
Synthesis of spacer-armed pseudodi-, pseudotetra-, and pseudohexasaccharides related to the capsular phosphoglycan of Haemophilus influenzae type a, the second most virulent serotype of H. influenzae (after type b), was performed for the first time via iterative chain elongation using H-phosphonate chemistry for the formation of inter-unit phosphodiester bridges. These compounds were prepared for the design of neoglycoconjugates, as exemplified by the transformation of the obtained pseudohexasaccharide derivative into a biotinylated glycoconjugate suitable for use in immunological studies, particularly in diagnostic screening systems as a coating antigen for streptavidin-coated plates and chip slides.
Библиографическая ссылка:
Kamneva A.A.
, Yashunsky D.V.
, Khatuntseva E.A.
, Nifantiev N.E.
Synthesis of Pseudooligosaccharides Related to the Capsular Phosphoglycan of Haemophilus influenzae Type a
Molecules. 2023. V.28. N15. 5688 . DOI: 10.3390/molecules28155688 WOS Scopus OpenAlex
Synthesis of Pseudooligosaccharides Related to the Capsular Phosphoglycan of Haemophilus influenzae Type a
Molecules. 2023. V.28. N15. 5688 . DOI: 10.3390/molecules28155688 WOS Scopus OpenAlex
Идентификаторы БД:
| ≡ Web of science: | WOS:001045653100001 |
| ≡ Scopus: | 2-s2.0-85167819026 |
| ≡ OpenAlex: | W4385346919 |