Реферат: An efficient method for the C(2)−H arylation of (benz)imidazoles and (benz)oxazoles with aryl chlorides and aryl bromides under Ni/NHC catalysis has been developed. The main benefit of the method is the in situ generation of active Ni/NHC complexes from the air-tolerant bench-stable precursors NiCl2Py2, IMes⋅HCl, and potassium tert-butoxide, which plays a dual role as base and Ni(II) to Ni(0) reductant. The approach represents a user-friendly alternative for procedures relying on the use of toxic phosphine ligands or unstable air-sensitive Ni(cod)2. The concept highlighted in the present study shows that mapping a competitive picture of catalyst dynamics and revealing the competitive processes towards the destruction and stabilization of catalytically active species enables a highly efficient catalytic system to be built under simple conditions.

Библиографическая ссылка: Khazipov O.V. , Shepelenko K.E. , Soliev S.B. , Nikolaeva K.A. , Chernyshev V.M. , Ananikov V.P.
Optimal Balance in the Catalyst Dynamics Enables C(2)−H Arylation of (Benz)imidazoles and (Benz)oxazoles by an In Situ‐Generated Ni/NHC System
Chemcatchem. 2022. V.14. N24. e202201055 . DOI: 10.1002/cctc.202201055 WOS Scopus OpenAlex

Идентификаторы БД:

Web of science:	WOS:000887995000001
Scopus:	2-s2.0-85142396259
OpenAlex:	W4306412176

Цитирование в БД:

БД	Цитирований
OpenAlex	7
Scopus	6
Web of science	5

Альметрики: