Direct and efficient electrocatalytic multicomponent assembling of arylaldehydes, malononitrile, and pyrazolin-5-ones into spirocyclopropyl pyrazolone scaffold

Direct and efficient electrocatalytic multicomponent assembling of arylaldehydes, malononitrile, and pyrazolin-5-ones into spirocyclopropyl pyrazolone scaffold Научная публикация

Журнал

Monatshefte Fur Chemie
ISSN: 1434-4475 , E-ISSN: 0026-9247

Вых. Данные

Год: 2021, Том: 152, Номер: 6, Страницы: 641-648 Страниц : 8 DOI: 10.1007/s00706-021-02784-w

Авторы

Elinson Michail N. ¹ , Ryzhkova Yuliya E. ¹ , Vereshchagin Anatoly N. ¹ , Ryzhkov Fedor V. ¹ , Kalashnikova Varvara M. ^1,2 , Egorov Mikhail P. ¹

Организации

1	N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow (Russian Federation)
2	D. I. Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation

The new electrochemical multicomponent assembling has been found: the electrolysis of arylaldehydes, malononitrile, and pyrazolin-5-ones in alcohols in an undivided cell in the presence of sodium bromide as mediator results in the formation of substituted 4-methyl-7-oxo-2-phenyl-5,6-diazaspiro[2.4]hept-4-ene-1,1-dicarbonitriles in 60–80% yields. The optimized reaction conditions and a mechanistic rationale for this electrocatalytic multicomponent assembling are presented.

Elinson M.N. , Ryzhkova Y.E. , Vereshchagin A.N. , Ryzhkov F.V. , Kalashnikova V.M. , Egorov M.P.
Direct and efficient electrocatalytic multicomponent assembling of arylaldehydes, malononitrile, and pyrazolin-5-ones into spirocyclopropyl pyrazolone scaffold
Monatshefte Fur Chemie. 2021. V.152. N6. P.641-648. DOI: 10.1007/s00706-021-02784-w WOS Scopus OpenAlex

Web of science:	WOS:000660333100001
Scopus:	2-s2.0-85107745605
OpenAlex:	W3167744964

БД	Цитирований
OpenAlex	7
Scopus	6
Web of science	5