Synthesis of highly functional imidazole derivatives via assembly of 2-unsubstituted imidazole N-oxides with CH-acids and arylglyoxals

Synthesis of highly functional imidazole derivatives via assembly of 2-unsubstituted imidazole N-oxides with CH-acids and arylglyoxals Full article

Journal

Tetrahedron
ISSN: 0040-4020 , E-ISSN: 1464-5416

Output data

Year: 2020, Volume: 76, Number: 8, Article number : 130947, Pages count : DOI: 10.1016/j.tet.2020.130947

Authors

Perevalov Valery P. ¹ , Mityanov Vitaly S. ^1,2 , Lichitsky Boris V. ² , Komogortsev Andrey N. ² , Kuz’mina Ludmila G. ³ , Koldaeva Tatyana Yu. ¹ , Miroshnikov Vladimir S. ¹ , Kutasevich Anton V. ¹

Affiliations

1	Department of Fine Organic Synthesis and Chemistry of Dyes, D. Mendeleyev University of Chemical Technology of Russia, Miusskaya Sq., 9, Moscow, 125047, Russian Federation
2	N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Pr., 47, Moscow, 119991, Russian Federation
3	Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Science, Leninskii Pr., 31, Moscow, 117907, Russian Federation

A novel and convenient method for the synthesis of a wide range of polyfunctional imidazole derivatives based on the three-component condensation of imidazole N-oxides with CH-acids and arylglyoxals has been developed. This reaction proceeds smoothly in moderate-to-good yields with a wide range of starting materials.

Perevalov V.P. , Mityanov V.S. , Lichitsky B.V. , Komogortsev A.N. , Kuz’mina L.G. , Koldaeva T.Y. , Miroshnikov V.S. , Kutasevich A.V.
Synthesis of highly functional imidazole derivatives via assembly of 2-unsubstituted imidazole N-oxides with CH-acids and arylglyoxals
Tetrahedron. 2020. V.76. N8. 130947 . DOI: 10.1016/j.tet.2020.130947 WOS Scopus OpenAlex

Web of science:	WOS:000515214500005
Scopus:	2-s2.0-85078500168
OpenAlex:	W2998838613

DB	Citing
OpenAlex	12
Scopus	11
Web of science	12