Nucleophilic Functionalization of 2-R-3-Nitropyridines as a Versatile Approach to Novel Fluorescent Molecules

Nucleophilic Functionalization of 2-R-3-Nitropyridines as a Versatile Approach to Novel Fluorescent Molecules Научная публикация

Журнал

Molecules
ISSN: 1420-3049

Вых. Данные

Год: 2022, Том: 27, Номер: 17, Номер статьи : 5692, Страниц : DOI: 10.3390/molecules27175692

Авторы

Nikol'skiy Vladislav V ¹ , Minyaev Mikhail E ¹ , Bastrakov Maxim A ¹ , Starosotnikov Alexey M ¹

Организации

1	N.D. Zelinsky Institute of Organic Chemistry RAS, Leninsky Prosp. 47, 11991 Moscow, Russia

A number of new 2-methyl- and 2-arylvinyl-3-nitropyridines were synthesized and their reactions with thiols were studied. It was found that 3-NO2 tends to be selectively substituted under the action of sulfur nucleophiles in the presence of another nucleofuge in position 5. Correlations between the substitution pattern and regioselectivity as well as photophysical properties were established. Some synthesized compounds possessed a large Stokes shift.

Nikol'skiy V.V. , Minyaev M.E. , Bastrakov M.A. , Starosotnikov A.M.
Nucleophilic Functionalization of 2-R-3-Nitropyridines as a Versatile Approach to Novel Fluorescent Molecules
Molecules. 2022. V.27. N17. 5692 . DOI: 10.3390/molecules27175692 WOS Scopus OpenAlex

Web of science:	WOS:000851717200001
Scopus:	2-s2.0-85137579284
OpenAlex:	W4295084378

БД	Цитирований
OpenAlex	3
Scopus	3
Web of science	3