Реферат: Green electrocatalytic multicomponent assembly of salicylaldehydes, kojic acid and malonic acid derivatives in n-propanol in the presence of potassium iodide as an electrolyte in an undivided cell results in the formation of 4-(3-hydroxy-6-(hydroxymethyl)-4-oxo-4H-pyran-2-yl) substituted 2-amino-4H-chromenes in 86–98 % yields. This new electrocatalytic multicomponent process is a facile and efficient environmentally benign way to the functionalized 2-amino-4H-chromenes, containing in the fourth position kojic acid fragment, which are perspective compounds for different biomedical applications, among them in the treatment of human inflammatory diseases. Python-automated docking procedure was carried out and the results support anti-inflammatory potential of the synthesized compounds.

Библиографическая ссылка: Ryzhkova Y.E. , Elinson M.N. , Vereshchagin A.N. , Kalashnikova V.M. , Korolev V.A. , Ryzhkov F.V. , Egorov M.P.
Green electrocatalytic Assembling of Salicylaldehydes, Kojic Acid, and Malonic Acid Derivatives into 2‐amino‐4H‐chromenes as Potent Anti‐inflammatory Agents
ChemistrySelect. 2022. V.7. N39. e202202872 . DOI: 10.1002/slct.202202872 WOS Scopus OpenAlex

Идентификаторы БД:

Web of science:	WOS:000869777100001
Scopus:	2-s2.0-85140256258
OpenAlex:	W4306790179

Цитирование в БД:

БД	Цитирований
OpenAlex	5
Scopus	5

Альметрики: