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Multicomponent protocol for the synthesis of substituted methyl 3-(3-hydroxy-4-oxo-4H-chromen-2-yl)propanoates from 3-hydroxy-4H-chromen-4-one Научная публикация

Журнал Synthetic Communications
ISSN: 1532-2432 , E-ISSN: 0039-7911
Вых. Данные Год: 2022, Том: 52, Номер: 16, Страницы: 1664-1671 Страниц : 8 DOI: 10.1080/00397911.2022.2107431
Авторы Komogortsev Andrey N. 1 , Melekhina Valeriya G. 1 , Lichitsky Boris V. 1
Организации
1 N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Science, Moscow, Russian Federation

Реферат: An efficient one-stage method for the preparation of substituted methyl 3-(3-hydroxy-4-oxo-4H-chromen-2-yl)propanoates was developed. The suggested approach based on multicomponent reaction of 3-hydroxy-4H-chromen-4-one with carbonyl compounds and Meldrum’s acid. The advantages of this synthesis are readily accessible starting materials, mild reaction conditions, atom economy and easy workup procedure, which can avoid chromatographic purifications. The structures of the obtained compounds were established by 1H, 13C-NMR spectroscopy and high-resolution mass spectrometry.
Библиографическая ссылка: Komogortsev A.N. , Melekhina V.G. , Lichitsky B.V.
Multicomponent protocol for the synthesis of substituted methyl 3-(3-hydroxy-4-oxo-4H-chromen-2-yl)propanoates from 3-hydroxy-4H-chromen-4-one
Synthetic Communications. 2022. V.52. N16. P.1664-1671. DOI: 10.1080/00397911.2022.2107431 WOS Scopus OpenAlex
Идентификаторы БД:
Web of science: WOS:000836117300001
Scopus: 2-s2.0-85135529765
OpenAlex: W4289745520
Цитирование в БД:
БД Цитирований
OpenAlex 1
Scopus 1
Web of science 1
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