Structures of the O‐antigens of Proteus bacilli belonging to OX group (serogroups O1–O3) used in Weil‐Felix test

Structures of the O‐antigens of Proteus bacilli belonging to OX group (serogroups O1–O3) used in Weil‐Felix test Full article

Journal

FEBS Letters
ISSN: 0014-5793 , E-ISSN: 1873-3468

Output data

Year: 1997, Volume: 411, Number: 2-3, Pages: 221-224 Pages count : 4 DOI: 10.1016/s0014-5793(97)00694-7

Authors

Ziolkowski Andrzej ¹ , Shashkov Alexander S. ² , Swierzko Anna St. ¹ , Senchenkova Sof'ya N. ² , Toukach Filip V. ² , Cedzynski Maciej ¹ , Amano Ken-Ichi ³ , Kaca Wieslaw ¹ , Knirel Yuriy A. ²

Affiliations

1	Center of Microbiology and Virology, Polish Academy of Sciences, ul. Lodowa 106, 93-232 Lodz, Poland
2	N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky pr. 47, 117913 Moscow, Russia
3	Central Research Laboratory, Akita University, School of Medicine, 1-1-1 Hondo, Akita 010, Japan

Structures of the O-specific polysaccharide chains of lipopolysaccharides from Proteus group OX strains (serogroups O1–O3) used as antigens in Weil-Felix test for diagnosis of rickettsiosis, were established. From them, the acid-labile polysaccharide of Proteus vulgaris OX19 (O1) is built up of the following branched pentasaccharide repeating units connected via a phosphate group: where QuiNAc stands for 2-acetamido-2,6-dideoxyglucose (N-acetylquinovosamine). The basis of serospecificity of the Proteus group OX antigens and their cross-reactivity with human anti-rickettsial antibodies is discussed.

Ziolkowski A. , Shashkov A.S. , Swierzko A.S. , Senchenkova S.N. , Toukach F.V. , Cedzynski M. , Amano K-I. , Kaca W. , Knirel Y.A.
Structures of the O‐antigens of Proteus bacilli belonging to OX group (serogroups O1–O3) used in Weil‐Felix test
FEBS Letters. 1997. V.411. N2-3. P.221-224. DOI: 10.1016/s0014-5793(97)00694-7 WOS Scopus OpenAlex

≡ Web of science:	WOS:A1997XN02400014
≡ Scopus:	2-s2.0-0031567580
≡ OpenAlex:	W2113815966