Annulation of aliphatic nitro compounds with β-styryl sulfonium salts toward the synthesis of isoxazoline N -oxides

Annulation of aliphatic nitro compounds with β-styryl sulfonium salts toward the synthesis of isoxazoline N -oxides Научная публикация

Журнал

Organic & Biomolecular Chemistry
ISSN: 1477-0520 , E-ISSN: 1477-0539

Вых. Данные

Год: 2026, Том: 24, Страницы: 2725–2731 Страниц : DOI: 10.1039/d6ob00176a

Авторы

Ushakov Pavel Yu. ¹ , Sukhorukov Alexey Yu. ¹ , Tabolin Andrey A. ¹ , Chichulin Stepan N. ^1,2

Организации

1	N. D. Zelinsky Institute of Organic Chemistry, 119991, Leninsky prospect, 47, Moscow, Russian Federation
2	Department of Chemistry, M. V. Lomonosov Moscow State University, 119991Leninskie gory, 1, str. 3, Moscow, Russian Federation

Vinyl sulfonium salts have proved to be convenient building blocks in modern organic synthesis due to the wide variety of their reactivities. In this study, we expand the spectrum of possible transformations using the annulation reaction with aliphatic nitro compounds as bis-nucleophilic species. The resulting isoxazoline N-oxides, which exhibit a previously difficult-to-obtain substitution pattern, turned out to be convenient precursors of valuable hydroxy ketones and polysubstituted isoxazolines.

Ushakov P.Y. , Sukhorukov A.Y. , Tabolin A.A. , Chichulin S.N.
Annulation of aliphatic nitro compounds with β-styryl sulfonium salts toward the synthesis of isoxazoline N -oxides
Organic & Biomolecular Chemistry. 2026. V.24. P.2725–2731. DOI: 10.1039/d6ob00176a WOS Scopus OpenAlex

Поступила в редакцию:	30 янв. 2026 г.
Принята к публикации:	5 мар. 2026 г.
Опубликована online:	10 мар. 2026 г.

≡ Web of science:	WOS:001716867500001
≡ Scopus:	2-s2.0-105033032463
≡ OpenAlex:	W7134930877