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Light-induced radical addition to oximes: a general route to branched primary amines Научная публикация

Журнал Chemical Science
ISSN: 2041-6520 , E-ISSN: 2041-6539
Вых. Данные Год: 2026, DOI: 10.1039/d6sc05310f
Авторы Rubanov Zakhar M. 1 , Levin Vitalij V. 1 , Dilman Alexander D. 1
Организации
1 N. D. Zelinsky Institute of Organic Chemistry, Leninsky Prosp. 47, 119991 Moscow, Russian Federation

Реферат: A platform for the synthesis of branched primary amines via radical addition to unprotected oximes is described. Readily available alkyl iodides, alkanes, and carboxylic acids were used as radical precursors through XAT, HAT, and LMCT activation modes. The key feature is the use of a Brønsted acid to activate the radical addition step and to suppress side reactions. This approach is suitable for one-pot carbonyl alkylative amination, a transformation that was previously unavailable for the synthesis of primary amines.
Библиографическая ссылка: Rubanov Z.M. , Levin V.V. , Dilman A.D.
Light-induced radical addition to oximes: a general route to branched primary amines
Chemical Science. 2026. DOI: 10.1039/d6sc05310f WOS Scopus OpenAlex
Даты:
Поступила в редакцию: 24 июн. 2026 г.
Принята к публикации: 5 авг. 2026 г.
Опубликована online: 6 авг. 2026 г.
Идентификаторы БД:
≡ Web of science: WOS:001848048100001
≡ Scopus: 2-s2.0-105047971876
≡ OpenAlex: W7197007544
Альметрики: