Photoinduced Synthesis of Iododifluoromethyl Sulfides from Organic Thiocyanates via Difluorinated Phosphonium Salts

Photoinduced Synthesis of Iododifluoromethyl Sulfides from Organic Thiocyanates via Difluorinated Phosphonium Salts Full article

Journal

Journal of Organic Chemistry
ISSN: 1520-6904 , E-ISSN: 0022-3263

Output data

Year: 2026, Volume: 91, Number: 32, Pages: 11135-11140 Pages count : 6 DOI: 10.1021/acs.joc.6c01393

Authors

Lozhkin Gregory A. ^1,2 , Trifonov Alexey L. ² , Dilman Alexander D. ²

Affiliations

1	Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1−3, 119991 Moscow, Russian Federation
2	N. D. Zelinsky Institute of Organic Chemistry, Leninsky Prospekt 47, 119991 Moscow, Russian Federation

A protocol for the synthesis of iododifluoromethyl sulfides from thiocyanates has been described. The method involves the formation of gem-difluorinated phosphonium salts from organic thiocyanates, difluorocarbene, and triphenylphosphine, followed by photoinduced phosphorus/iodine exchange. The photoreaction does not require a photocatalyst. The method allows the assembly of a similar ICF2-substituted selenide, as well as sulfides bearing the BrCF2 and ClCF2 groups.

Lozhkin G.A. , Trifonov A.L. , Dilman A.D.
Photoinduced Synthesis of Iododifluoromethyl Sulfides from Organic Thiocyanates via Difluorinated Phosphonium Salts
Journal of Organic Chemistry. 2026. V.91. N32. P.11135-11140. DOI: 10.1021/acs.joc.6c01393 WOS Scopus OpenAlex

Submitted:	Jun 12, 2026
Published online:	Aug 14, 2026

≡ Web of science:	WOS:001837541000001
≡ Scopus:	2-s2.0-105047320922
≡ OpenAlex:	W7172412571