Conformational Lability of Bispidine as a Route to New Polycyclic Compounds | Sciact

Conformational Lability of Bispidine as a Route to New Polycyclic Compounds Научная публикация

Журнал

Journal of Organic Chemistry
ISSN: 1520-6904 , E-ISSN: 0022-3263

Вых. Данные

Год: 2026, DOI: 10.1021/acs.joc.6c01744

Авторы

Medved'ko Aleksei V. ¹ , Vatsadze Sergey Z. ¹

Организации

1	Zelinsky Institute of Organic Chemistry RAS, 119991 N.D. Moscow, Russia

In this study, novel tricyclic compounds based on bispidine were prepared via a Michael addition−Henry domino reaction. This reaction sequence proceeds under mild conditions with high diastereoselectivity. Postsynthetic transformation pathways for the resulting nitro alcohols were demonstrated, leading to tricyclic amino alcohols of various structures.

Medved'ko A.V. , Vatsadze S.Z.
Conformational Lability of Bispidine as a Route to New Polycyclic Compounds
Journal of Organic Chemistry. 2026. DOI: 10.1021/acs.joc.6c01744

Поступила в редакцию:	20 июл. 2026 г.
Принята к публикации:	13 окт. 2026 г.
Опубликована в печати:	20 окт. 2026 г.

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