Fullerenyl-1,2,3-Triazoles: Synthesis and Cytotoxic Activity | Sciact

Fullerenyl-1,2,3-Triazoles: Synthesis and Cytotoxic Activity Научная публикация

Журнал

Chemistry proceedings
ISSN: 2673-4583

Вых. Данные

Год: 2022, Том: 8, Номер: 1, Номер статьи : 96, Страниц : DOI: 10.3390/ecsoc-25-11659

Авторы

Sadretdinova Zarema R. ¹ , Akhmetov Arslan R. ¹ , Dzhemileva Lilya U. ² , D’yakonov Vladimir A. ² , Tuktarov Airat ³ , Dzhemilev Usein ²

Организации

1	Institute of Petrochemistry and Catalysis of RAS, Ufa 450075, Russia
2	Institute of Organic Chemistry Named after N. D. Zelinsky of RAS, Moscow 119991, Russia
3	Limited Liability Company “Gazpromneft-Industrial Innovations”, Saint Petersburg 197350, Russia

Through the reaction of fullerenylazide with terminal acetylenes, previously undescribed 1-butyl-2-triazolylfullerenes, in which the heterocyclic fragment was directly attached to the fullerene backbone, were synthesized for the first time. Water-soluble complexes of the synthesized adducts of fullerene with polyvinylpyrrolidone showed a high cytotoxic activity towards tumor cells of the Jurkat, K562, and U937 lines.

Sadretdinova Z.R. , Akhmetov A.R. , Dzhemileva L.U. , D’yakonov V.A. , Tuktarov A. , Dzhemilev U.
Fullerenyl-1,2,3-Triazoles: Synthesis and Cytotoxic Activity
Chemistry proceedings. 2022. V.8. N1. 96 . DOI: 10.3390/ecsoc-25-11659 OpenAlex

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