Fullerenyl-1,2,3-Triazoles: Synthesis and Cytotoxic Activity

Fullerenyl-1,2,3-Triazoles: Synthesis and Cytotoxic Activity Full article

Journal

Chemistry proceedings
ISSN: 2673-4583

Output data

Year: 2022, Volume: 8, Number: 1, Article number : 96, Pages count : DOI: 10.3390/ecsoc-25-11659

Authors

Sadretdinova Zarema R. ¹ , Akhmetov Arslan R. ¹ , Dzhemileva Lilya U. ² , D’yakonov Vladimir A. ² , Tuktarov Airat ³ , Dzhemilev Usein ²

Affiliations

1	Institute of Petrochemistry and Catalysis of RAS, Ufa 450075, Russia
2	Institute of Organic Chemistry Named after N. D. Zelinsky of RAS, Moscow 119991, Russia
3	Limited Liability Company “Gazpromneft-Industrial Innovations”, Saint Petersburg 197350, Russia

Through the reaction of fullerenylazide with terminal acetylenes, previously undescribed 1-butyl-2-triazolylfullerenes, in which the heterocyclic fragment was directly attached to the fullerene backbone, were synthesized for the first time. Water-soluble complexes of the synthesized adducts of fullerene with polyvinylpyrrolidone showed a high cytotoxic activity towards tumor cells of the Jurkat, K562, and U937 lines.

Sadretdinova Z.R. , Akhmetov A.R. , Dzhemileva L.U. , D’yakonov V.A. , Tuktarov A. , Dzhemilev U.
Fullerenyl-1,2,3-Triazoles: Synthesis and Cytotoxic Activity
Chemistry proceedings. 2022. V.8. N1. 96 . DOI: 10.3390/ecsoc-25-11659 OpenAlex

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