The multicomponent synthesis of urea substituted 2-arylfurans | Sciact

The multicomponent synthesis of urea substituted 2-arylfurans Научная публикация

Журнал

Tetrahedron
ISSN: 0040-4020 , E-ISSN: 1464-5416

Вых. Данные

Год: 2022, Том: 111, Номер статьи : 132716, Страниц : DOI: 10.1016/j.tet.2022.132716

Авторы

Komogortsev Andrey N. ¹ , Melekhina Valeriya G. ¹ , Lichitsky Boris V. ¹ , Migulin Vasily A. ¹ , Karibov Turan T. ¹ , Minyaev Mikhail E. ¹

Организации

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Pr., 47, Moscow, 119991, Russian Federation

For the first time, we elaborated a one-step approach for the synthesis of 2-arylfurans containing urea moiety. The proposed method is based on multicomponent condensation of various carbo- and heterocyclic enols, arylglyoxals and cyanamide. The considered approach is general and allows one to use the various enol derivatives as starting compounds. The advantages of the studied method are the use of readily available starting compounds, atom economy, easy work-up procedure without chromatographic purification. The structure of one of synthesized products was determined by X-Ray diffraction.

Komogortsev A.N. , Melekhina V.G. , Lichitsky B.V. , Migulin V.A. , Karibov T.T. , Minyaev M.E.
The multicomponent synthesis of urea substituted 2-arylfurans
Tetrahedron. 2022. V.111. 132716 . DOI: 10.1016/j.tet.2022.132716 WOS Scopus OpenAlex

Web of science:	WOS:000788821200002
Scopus:	2-s2.0-85125910071
OpenAlex:	W4220816991

БД	Цитирований
OpenAlex	10
Scopus	10
Web of science	9