‘On-solvent’ new domino reaction of salicylaldehyde, malononitrile and 4-hydroxy-6-methylpyridin-2(1 H )-one: fast and efficient approach to medicinally relevant 4-pyridinyl-2-amino-4 H -chromene scaffold Научная публикация
| Журнал |
Mendeleev Communications
ISSN: 1364-551X , E-ISSN: 0959-9436 |
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| Вых. Данные | Год: 2017, Том: 27, Номер: 6, Страницы: 559-561 Страниц : 3 DOI: 10.1016/j.mencom.2017.11.006 | ||
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Реферат:
Sodium acetate catalyzed assembling of salicylaldehydes, malononitrile and 4-hydroxy-6-methylpyridin-2(1H)-one in small amount of ethanol gives rapidly (5 min) substituted 4-pyridinyl-2-amino-4H-chromenes in 82–99% yields. This novel domino reaction opens the fast, facile, and flexible way to the new type of functionalized 2-amino-4H-chromene scaffold containing uracil-like moiety, which are relevant compounds for diverse biomedical applications.
Библиографическая ссылка:
Elinson M.N.
, Ryzhkov F.V.
, Vereshchagin A.N.
, Korshunov A.D.
, Novikov R.A.
, Egorov M.P.
‘On-solvent’ new domino reaction of salicylaldehyde, malononitrile and 4-hydroxy-6-methylpyridin-2(1 H )-one: fast and efficient approach to medicinally relevant 4-pyridinyl-2-amino-4 H -chromene scaffold
Mendeleev Communications. 2017. V.27. N6. P.559-561. DOI: 10.1016/j.mencom.2017.11.006 WOS Scopus OpenAlex
‘On-solvent’ new domino reaction of salicylaldehyde, malononitrile and 4-hydroxy-6-methylpyridin-2(1 H )-one: fast and efficient approach to medicinally relevant 4-pyridinyl-2-amino-4 H -chromene scaffold
Mendeleev Communications. 2017. V.27. N6. P.559-561. DOI: 10.1016/j.mencom.2017.11.006 WOS Scopus OpenAlex
Идентификаторы БД:
| Web of science: | WOS:000418983900006 |
| Scopus: | 2-s2.0-85035066146 |
| OpenAlex: | W2768683583 |