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Antimalarial and Anticancer Activity Evaluation of Bridged Ozonides, Aminoperoxides, and Tetraoxanes Научная публикация

Журнал ChemMedChem
ISSN: 1860-7179 , E-ISSN: 1860-7187
Вых. Данные Год: 2022, Том: 17, Номер: 20, Номер статьи : e202200328, Страниц : DOI: 10.1002/cmdc.202200328
Авторы Coghi Paolo 1 , Yaremenko Ivan A. 2 , Prommana Parichat 3 , Wu Jia Ning 4 , Zhang Rui Long 4 , Ng Jerome P.L . 4 , Belyakova Yulia Yu. 2 , Law Betty Yuen Kwan 4 , Radulov Peter S . 2 , Uthaipibull Chairat 3,5 , Wong Vincent K.W . 4 , Terent'ev Alexander O. 2
Организации
1 Macau University of Science and Technology, State Key Laboratory of Quality Research in Chinese Medicines, Avenida wai long, N/A, macau, MACAU.
2 N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, Moscow, 119991 Russia
3 National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), 113 Thailand Science Park, Pathum Thani, 12120 Thailand
4 Neher's Biophysics Laboratory for Innovative Drug Discovery State Key Laboratory of Quality Research in Chinese Medicine Macau University of Science and Technology Avenida Wai Long, Taipa Macau P.R. China
5 Thailand Center of Excellence for Life Sciences (TCELS), Bangkok, Thailand

Реферат: Bridged aminoperoxides exhibit good activity and selectivity toward the A549 lung cancer cell line. Bridged ozonides demonstrate high antimalarial activity in vitro and selectivity against the chloroquine-resistant P. falciparum strain K1. Ozonides induce apoptosis in HepG2 cells through a reactive oxygen species (ROS)-independent dysfunction pathway.
Библиографическая ссылка: Coghi P. , Yaremenko I.A. , Prommana P. , Wu J.N. , Zhang R.L. , Ng J.P.L. , Belyakova Y.Y. , Law B.Y.K. , Radulov P.S. , Uthaipibull C. , Wong V.K.W. , Terent'ev A.O.
Antimalarial and Anticancer Activity Evaluation of Bridged Ozonides, Aminoperoxides, and Tetraoxanes
ChemMedChem. 2022. V.17. N20. e202200328 . DOI: 10.1002/cmdc.202200328 WOS Scopus OpenAlex
Идентификаторы БД:
Web of science: WOS:000857951100001
Scopus: 2-s2.0-85138436799
OpenAlex: W4294127577
Цитирование в БД:
БД Цитирований
OpenAlex 16
Scopus 16
Web of science 13
Альметрики: