A Novel Entry to 3,4,5-Trisubstituted 2-Pyrrolidones from Isoxazoline-N-oxides

A Novel Entry to 3,4,5-Trisubstituted 2-Pyrrolidones from Isoxazoline-N-oxides Научная публикация

Журнал

Synlett
ISSN: 0936-5214 , E-ISSN: 1437-2096

Вых. Данные

Год: 2018, Том: 29, Номер: 14, Страницы: 1871-1874 Страниц : 4 DOI: 10.1055/s-0037-1610213

Авторы

Zhmurov Petr A. ¹ , Ushakov Pavel Yu. ¹ , Novikov Roman A. ^1,2 , Sukhorukov Alexey Yu. ¹ , Ioffe Sema L. ¹

Организации

1	N. D. Zelinsky Institute of Organic Chemistry
2	Department of Chemistry, M. V. Lomonosov Moscow State University

A novel strategy for the synthesis of stereochemically defined 3,4,5-trisubstituted 2-pyrrolidones was developed. The suggested approach involves reductive domino-type recyclization of 3-aminomethyl-substituted isoxazolines as a key stage. The latter are prepared via α-C–H functionalization of readily available isoxazoline-N-oxides.

Zhmurov P.A. , Ushakov P.Y. , Novikov R.A. , Sukhorukov A.Y. , Ioffe S.L.
A Novel Entry to 3,4,5-Trisubstituted 2-Pyrrolidones from Isoxazoline-N-oxides
Synlett. 2018. V.29. N14. P.1871-1874. DOI: 10.1055/s-0037-1610213 WOS Scopus OpenAlex

Web of science:	WOS:000442304600012
Scopus:	2-s2.0-85051941775
OpenAlex:	W2886953673

БД	Цитирований
OpenAlex	13
Scopus	12
Web of science	11