Synthesis of Difluoroalkylated Heteroarenes via Difluorocarbene Научная публикация
| Журнал |
Organic Letters
ISSN: 1523-7060 , E-ISSN: 1523-7052 |
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| Вых. Данные | Год: 2021, Том: 23, Номер: 17, Страницы: 6977-6981 Страниц : 5 DOI: 10.1021/acs.orglett.1c02603 | ||
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Реферат:
A diversity-oriented and C2-selective synthesis of difluoroalkyl-substituted heteroarenes from three fragments, N-methoxyazinium salts, difluorocarbene, and electrophilic or radical reagents, is described. The reaction proceeds via the addition of difluorinated phosphorus ylide to in situ methylated heteroarene N-oxides, leading to phosphonium salts, which can undergo further transformations under basic or photoinduced conditions.
Библиографическая ссылка:
Trifonov A.L.
, Dilman A.D.
Synthesis of Difluoroalkylated Heteroarenes via Difluorocarbene
Organic Letters. 2021. V.23. N17. P.6977-6981. DOI: 10.1021/acs.orglett.1c02603 WOS Scopus OpenAlex
Synthesis of Difluoroalkylated Heteroarenes via Difluorocarbene
Organic Letters. 2021. V.23. N17. P.6977-6981. DOI: 10.1021/acs.orglett.1c02603 WOS Scopus OpenAlex
Идентификаторы БД:
| Web of science: | WOS:000693633500073 |
| Scopus: | 2-s2.0-85114661296 |
| OpenAlex: | W3195930966 |