'Solvent-free’ and 'on-solvent’ multicomponent reaction of isatins, malononitrile, and bicyclic CH-acids: fast and efficient way to medicinal privileged spirooxindole scaffold Научная публикация
| Журнал |
Arkivoc
ISSN: 1551-7012 , E-ISSN: 1551-7004 |
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| Вых. Данные | Год: 2018, Том: 2018, Номер: 4, Страницы: 276-285 Страниц : 10 DOI: 10.24820/ark.5550190.p010.640 | ||
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| Организации |
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Реферат:
The fast (15 min) PASE-'solvent-free' and 'on-solvent' multicomponent reactions of isatins, malononitrile and
bicyclic CH-acids catalyzed by sodium acetate result in efficient formation of substituted spiro-oxindoles in 90–
98% yields. These methods are fast multicomponent approaches to the spiro-oxindoles, substances with
promising anticancer activities. These new 'solvent-free' and 'on-solvent' techniques reduce solvent use,
thereby leading to reduced waste, in connection with a new concept of solvent-assisted domino-reaction
strategy.
Библиографическая ссылка:
Elinson M.N.
, Vereshchagin A.N.
, Ryzhkov F.V.
, Anisina Y.E.
'Solvent-free’ and 'on-solvent’ multicomponent reaction of isatins, malononitrile, and bicyclic CH-acids: fast and efficient way to medicinal privileged spirooxindole scaffold
Arkivoc. 2018. V.2018. N4. P.276-285. DOI: 10.24820/ark.5550190.p010.640 WOS Scopus OpenAlex
'Solvent-free’ and 'on-solvent’ multicomponent reaction of isatins, malononitrile, and bicyclic CH-acids: fast and efficient way to medicinal privileged spirooxindole scaffold
Arkivoc. 2018. V.2018. N4. P.276-285. DOI: 10.24820/ark.5550190.p010.640 WOS Scopus OpenAlex
Идентификаторы БД:
| Web of science: | WOS:000441863800021 |
| Scopus: | 2-s2.0-85056868142 |
| OpenAlex: | W2924404473 |