Trifluoromethyl-substituted 1,6-naphthyridines and pyrido[4,3-d]pyrimidines | Sciact

Trifluoromethyl-substituted 1,6-naphthyridines and pyrido[4,3-d]pyrimidines Научная публикация

Журнал

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Вых. Данные

Год: 2013, Том: 62, Номер: 5, Страницы: 1255-1261 Страниц : 7 DOI: 10.1007/s11172-013-0173-3

Авторы

Vasil’ev L.S. ¹ , Surzhikov F.E. ¹ , Baranin S.V. ¹ , Dorokhov V.A. ¹

Организации

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

A convenient method for the synthesis of 1-alkyl-5-trifluoromethyl-1,6-naphthyridin-4(1H)-ones was elaborated based on the reaction of 4-alkylamino-3-trifluoroacetimidoyl-3-penten-2-one diphenylboron chelates with dimethylformamide dimethyl acetal. 3-Acetyl-4-amino-2-trifluoromethylpyridine was used to obtain 5-trifluoromethyl-1,6-naphthyridin-4(1H)-one and its 2-methoxycarbonyl derivative, as well as 4-methyl-5-trifluoromethylpyrido-[4,3-d]pyrimidine.

Vasil’ev L.S. , Surzhikov F.E. , Baranin S.V. , Dorokhov V.A.
Trifluoromethyl-substituted 1,6-naphthyridines and pyrido[4,3-d]pyrimidines
Russian Chemical Bulletin. 2013. V.62. N5. P.1255-1261. DOI: 10.1007/s11172-013-0173-3 WOS Scopus OpenAlex

≡ Web of science:	WOS:000332793600018
≡ Scopus:	2-s2.0-84894643753
≡ OpenAlex:	W2010007729