2,4-Dihydroxypentanoic Acids: New Non-sugar Components of Bacterial Polysaccharides

2,4-Dihydroxypentanoic Acids: New Non-sugar Components of Bacterial Polysaccharides Full article

Journal

Natural Product Communications
ISSN: 1555-9475 , E-ISSN: 1934-578X

Output data

Year: 2008, Volume: 3, Number: 10, Article number : 1934578X0800301, Pages count : DOI: 10.1177/1934578x0800301009

Authors

Shashkov Alexander S. ¹ , Kocharova Nina A. ¹ , Toukach Filip V. ¹ , Kachala Vadim V. ¹ , Knirel Yuriy A. ¹

Affiliations

1	N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia

New components of bacterial polysaccharides, (2S,4R)- and (2R,4R)-2,4-dihydroxypentanoic acids, were identified using two-dimensional 1H and 13C NMR spectroscopy in the O-antigens of Providencia alcalifaciens O8 and O31. The acids were ether-linked via their 2-HO-group to a residue of either N-acetylglucosamine or mannose at position 4. The absolute configurations of the acids were determined by NOE spectroscopy, combined with molecular modeling.

Shashkov A.S. , Kocharova N.A. , Toukach F.V. , Kachala V.V. , Knirel Y.A.
2,4-Dihydroxypentanoic Acids: New Non-sugar Components of Bacterial Polysaccharides
Natural Product Communications. 2008. V.3. N10. 1934578X0800301 . DOI: 10.1177/1934578x0800301009 Scopus OpenAlex

≡ Scopus:	2-s2.0-62549152370
≡ OpenAlex:	W2926544706