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Electrocatalytic multicomponent transformation of cyclic 1,3-diketones, isatins, and malononitrile: facile and convenient way to functionalized spirocyclic (5,6,7,8-tetrahydro-4H-chromene)-4,3′-oxindole system Научная публикация

Журнал Tetrahedron
ISSN: 0040-4020 , E-ISSN: 1464-5416
Вых. Данные Год: 2007, Том: 63, Номер: 42, Страницы: 10543-10548 Страниц : 6 DOI: 10.1016/j.tet.2007.07.080
Авторы Elinson Michail N. 1 , Ilovaisky Alexey I. 1 , Dorofeev Alexander S. 1 , Merkulova Valentina M. 1 , Stepanov Nikita O. 1 , Miloserdov Fedor M. 1 , Ogibin Yuri N. 1 , Nikishin Gennady I. 1
Организации
1 N. D. Zelinsky Institute of Organic Chemistry, Leninsky prospect 47, 119991 Moscow, Russia

Реферат: An electrochemically induced catalytic multicomponent transformation of cyclic 1,3-diketones, isatins, and malononitrile in alcohols in an undivided cell in the presence of sodium bromide as an electrolyte results in the formation of spirooxindoles with fused functionalized 5,6,7,8-tetrahydro-4H-chromene system in 83–98% yields. The application of this efficient electrocatalytic method to the formation of medicinally relevant spirocyclic (4H-chromene)-4,3′-oxindoles is beneficial from the viewpoint of diversity-oriented large-scale processes and represents novel, facile, and environmentally benign synthetic concept for multicomponent reaction strategy.
Библиографическая ссылка: Elinson M.N. , Ilovaisky A.I. , Dorofeev A.S. , Merkulova V.M. , Stepanov N.O. , Miloserdov F.M. , Ogibin Y.N. , Nikishin G.I.
Electrocatalytic multicomponent transformation of cyclic 1,3-diketones, isatins, and malononitrile: facile and convenient way to functionalized spirocyclic (5,6,7,8-tetrahydro-4H-chromene)-4,3′-oxindole system
Tetrahedron. 2007. V.63. N42. P.10543-10548. DOI: 10.1016/j.tet.2007.07.080 WOS Scopus OpenAlex
Идентификаторы БД:
Web of science: WOS:000252092300017
Scopus: 2-s2.0-34548314643
OpenAlex: W2040962232
Цитирование в БД:
БД Цитирований
OpenAlex 84
Scopus 99
Web of science 99
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